Hollywood isn't always what it's cracked up to be. Sometimes the characters playing best friends on screen actually hate each other in real life. The Drama that goes on when the camera is not rolling is often what tears apart a well functioning television show. Check out some huge stars that went crazy and ended up getting canned.
The lifestyle that Charlie Sheen was eventually going to have its consequences. He was the star of the television show Two and a Half Men when he decided to attack the show's creators in a little more crazy or style that was usual for the actor. He went on an anti-Semitic rant calling them all sorts of names and even physically threatened them. Needless to say this show fired Charlie from the show and killed of his character in a very crazy way.